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DYRK3, active, GST tagged human

品牌
Sigma-Aldrich
CAS
174206-56-5
货号
SRP5331
规格纯度
PRECISIO®, recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
参考价格
6468.88 *本价格含增值税费
促销
服务
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数量
-+
产品名称:
174206-56-5
DYRK3, active, GST tagged human
REDK
DYRK5
RED
产品介绍:

产品说明

一般描述

DYRK3 or dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 is belongs to the DYRK family of dual-specificity protein kinases that catalyze autophosphorylation on serine/threonine and tyrosine residues. DYRK3 expressed in E. coli undergoes tyrosine autophosphorylation and catalyzes phosphorylation of histones H3 and H2B in vitro. DYRK3 regulate different steps of the caveolar cycle. DYRK3 can promote cell survival through phosphorylation and activation of SIRT1. DYRK3 directly phosphorylate SIRT1 at Thr(522), promoting deacetylation of p53.

外形

Supplied in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.

制备说明

After opening, aliquot into smaller quantities and store at -70 ℃. Avoid repeating handling and multiple freeze/thaw cycles.

法律信息

PRECISIO is a registered trademark of sigma-aldrich Co. LLC

基本信息

NACRESNA.32

产品性质

生物来源human
重组expressed in E. coli
产品线PRECISIO®
测定≥70% (SDS-PAGE)
形式buffered aqueous glycerol solution
specific activity194-290 nmol/min·mg
分子量 ~95 kDa
technique(s)cell culture | mammalian: suitable
NCBI登记号NM_001004023
运输dry ice
储存温度−70℃
Gene Informationhuman ... DYRK3(8444)

安全信息

储存分类代码10 - Combustible liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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