LCAT activator compound A

产品名称：

1000269-30-6
LCAT activator compound A
3-[[5-(Ethylthio)-1,3,4-thiadiazol-2-yl]thio]pyrazine-2-carbonitrile
Compound A
3-[[5-(Ethylthio)-1,3,4-thiadiazol-2-yl]thio]-2-pyrazinecarbonitrile

产品介绍：

产品说明

生化/生理作用

LCAT activator compound A is an activator of Lecithin:cholesterol acyltransferase (LCAT) including some mutant LCATs found in Familial LCAT Deficiency (FLD). LCAT activator compound A forms a covalent hydrophobic adduct with LCAT Cys 31. The chronic treatment with LCAT activator compound A results in a significant increase in HDLc, HDL particle, size, plasma apolipoprotein A-I level, plasma cholesteryl ester to free cholesterol ratio, and a significant reduction in very low-density lipoprotein cholesterol in hamsters.

基本信息

经验(实验)分子式	C₉H₇N₅S₃
分子量	281.38
NACRES	NA.77

产品性质

测定	≥98% (HPLC)
形式	powder
颜色	white to brown
溶解性	DMSO: 2 mg/mL, clear
储存温度	−20℃
SMILES string	CCSC1=NN=C(S1)SC2=NC=CN=C2C#N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable