产品说明
一般描述
Calcyclin, also known as S100A6, is a calcium binding protein that is highly expressed in fibroblasts and epithelial cells. Inhibition of calcyclin by p53 is part of the mechanism to control cell proliferation. Calcyclin is associated with cancer and metastasis and plays a role in cell cycle regulation.
免疫原
Full length recombinant protein corresponding to human Calcyclin.
Material obtained from the National Cancer Institute’s Clinical Proteomic Technologies for Cancer (CPTC) program.
应用
Research Sub Category
GPCR, cAMP/cGMP & Calcium Signaling
Anti-Calcyclin Antibody, clone CPTC-Calcyclin-2 detects level of Calcyclin & has been published & validated for use in WB, ELISA, IH.
Research Category
Signaling
Immunohistochemistry Analysis: A previous lot was used by an independent laboratory in IH. (Tara Hitke, Developmental Studies Hybridoma Bank, University of Iowa.)
质量
Evaluated by Western Blot in human lung tissue lysate.
Western Blot Analysis: 0.5 µg/mL of this antibody detected Calcyclin on 10 µg of human lung tissue lysate.
目标描述
~10 kDa observed
外形
Format: Purified
Protein G
Purified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
储存及稳定性
Stable for 1 year at 2-8°C from date of receipt.
分析说明
Control
Human lung tissue lysate
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
产品性质
质量水平 | 100 |
生物来源 | mouse |
抗体形式 | purified immunoglobulin |
antibody product type | primary antibodies |
克隆 | CPTC-Calcyclin-2, monoclonal |
species reactivity | human |
technique(s) | ELISA: suitable immunohistochemistry: suitable western blot: suitable |
同位素/亚型 | IgG2aκ |
NCBI登记号 | NP_055439 |
UniProt登记号 | P06703 |
运输 | wet ice |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich