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Dkk-1, Rat, Recombinant

品牌
Sigma-Aldrich
货号
371208
规格纯度
Dkk-1, Rat, Recombinant, consists of amino acids 23-270, fused at the C-terminus to a His·Tag sequence, and expressed in NS0-derived mouse myeloma cells.
参考价格
7211.57 *本价格含增值税费
促销
服务
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数量
-+
产品名称:
Dkk-1, Rat, Recombinant
产品介绍:

产品说明

一般描述

Recombinant, rat Dickkopf related protein-1 (Dkk-1), consisting of amino acids 23-270, fused at the C-terminus to a His•Tag sequence, and expressed in NS0-derived mouse myeloma cells. The balance between Wnt signaling and Dkk-1 inhibition is essential for bone formation and homeostasis.
Dkk-1, Rat, Recombinant, consists of amino acids 23-270, fused at the C-terminus to a His•Tag sequence, and expressed in NS0-derived mouse myeloma cells.

包装

10 μg in Glass bottle

生化/生理作用

ND₅₀ = 0.1-0.5 µg/ml as measured by inhibition of Wnt-3a-induced (10 ng/ml rmWnt-3a) alkaline phosphatase production by proliferation of MC3T3-E1 mouse osteoblastic cells.

警告

Toxicity: Standard Handling (A)

外形

Lyophilized from 0.2 µm filtered PBS, BSA.

重悬

Following reconstitution refrigerate (4°C) for short-term storage or aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for up to 1 month at 4°C or for up to 3 months at -20°C.
Reconstitute to 100 µg/ml with sterile PBS containing ≥1% human or bovine serum albumin.

其他说明

Li, J. et al. 2006. Bone36, 754.
Morvan, F. et al. 2006. J. Bone Miner. Res.21, 934.
Niehrs, C. 2006. Oncogene25, 7469.
Verani, R. et al. 2006. J. Neurochem.101, 242.
Cappuccio, I. et al. 2005. J. Neurosci.25, 2647.
Kemp, C. et al. 2005. Dev. Dyn.233, 1064.
Adamska, M. et al. 2004. Dev. Biol.272, 134.
Bullock, C.M. et al. 2004. Mol. Pharmacol.65, 582.
Mao, B. et al. 2002. Nature417, 664.
Mao, B. et al. 2001. Nature411, 321.
Krupnik, V.E., et al. 1999. Gene238, 301.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

产品性质

重组expressed in mouse NSO cells
质量水平100
测定≥95% (SDS-PAGE)
形式lyophilized
manufacturer/tradenameCalbiochem®
储存条件OK to freeze
杂质≤1.0 EU/μg protein Endotoxin
运输ambient
储存温度−20℃

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 2

Sigma-Aldrich

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