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Anti-Insulin-Like Growth Factor-I Receptor antibody produced in goat

品牌
Sigma-Aldrich
货号
I7151
规格纯度
affinity isolated antibody, lyophilized powder
参考价格
6289.53 *本价格含增值税费
促销
服务
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  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-Insulin-Like Growth Factor-I Receptor antibody produced in goat
Anti-IGF-I R
产品介绍:

产品说明

一般描述

Insulin-Like Growth Factor-I Receptor (IGF-I receptor) is a disulfide-linked heterotetrameric transmembrane protein that belongs to Tyr protein kinase family and is expressed mainly in all cells and tissues. Association of two α (130 kD) and two β (95 kD) subunits of IGF-I receptor is essential for receptor autophosphorylation. It has a pivotal role in cell growth control as well as can induce differentiation, and eventually cell death, of certain types of cells. Anti-Insulin-Like Growth Factor-I Receptor antibody can be used to block cell surface IGF-I sR mediated IGF-I and IGF-II bioactivity. Goat anti-Insulin-Like Growth Factor-I Receptor antibody reacts specifically with recombinant human IGF-I. The product has shown no cross-reactivity for other cytokines tested.

特异性

The antibody blocks cell surface IGF-I R mediated IGF-I and IGF-II biological activity. At optimal antibody concentration, no more than 40-60% of the IGF-I or IGF-II activity can be blocked by this antibody.

免疫原

Recombinant human IGF-I soluble receptor expressed in Sf 21.

应用

Anti-Insulin-Like Growth Factor-I Receptor antibody can be used in indirect ELISA and western blotting.

外形

Lyophilized from 0.2 μm filtered solution of phosphate buffered saline with 5% trehalose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号MFCD00282340

产品性质

质量水平100
生物来源goat
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式lyophilized powder
species reactivityhuman
technique(s)indirect ELISA: suitable
neutralization: suitable
western blot: suitable
UniProt登记号P08069
储存温度−20℃
Gene Informationhuman ... IGF1R(3480)

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, type N95 (US)

Sigma-Aldrich

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