TIMP-2, Human Rheumatoid Synovial Fibroblast-Calbiochem

产品说明

一般描述

Native TIMP-2 from human rheumatoid synovial fibroblast. Member of a family of inhibitors that participate in the activation and regulation of MMP activity. Forms a non-covalent stoichiometric complex with latent and active MMPs. Shown to inhibit the activities of MMP-1, MMP-2, MMP-12, and transin.
Native TIMP-2 from human rheumatoid synovial fibroblast. Member of a family of inhibitors that participate in the activation and regulation of MMP activity. Forms a non-covalent stoichiometric complex with latent and active MMPs. Shown to inhibit the activities of MMP-1, MMP-2, MMP-12, and transin.

包装

5 μg in Plastic ampoule

生化/生理作用

Product does not compete with ATP.
Reversible: no
Primary Target
MMP-1
Cell permeable: no

警告

Toxicity: Standard Handling (A)

外形

In 200 mM NaCl, 50 mM Tris-HCl, 5 mM CaCl₂, 1 µM ZnCl₂, 0.05% BRIJ^® 35 Detergent, pH 7.0.

制备说明

Prepared from fibroblasts that have been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

其他说明

Greene, J., et al. 1996. J. Biol. Chem. 271, 30375.
Miyazaki, K., et al. 1993. J. Biol. Chem. 268, 14387.

法律信息

Brij is a registered trademark of Croda International PLC
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

产品性质

安全信息