4′,7-Dihydroxy 6-(3-methyl 2-butenyl)flavanone

产品名称：

19879-32-4
Bavachin
(2S)-2,3-Dihydro-7-hydroxy-2-(4-hydroxyphenyl)-6-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one
Corylifolin
4′,7-Dihydroxy 6-(3-methyl 2-butenyl)flavanone

产品介绍：

产品说明

生化/生理作用

Bavachin is a flavonoid isolated from seeds of Psoralea corylifolia. It is a phytoestrogen that activates ERα and ERβ (EC50s = 320 and 680 nM, respectively), stimulates osteoblast proliferation and differentiation, and prevents bone loss following ovariectomy in rats.
Bavachin is an inhibitor of acyl coenzyme A: cholesterol acyltransferase (ACAT). The IC50 value of bavachin was reported to be 86.0 μM in ACAT assay system using rat liver microsome.
Bavachin is also reported to increase insulin-induced glucose uptake by differentiated adipocytes and myoblasts.

物理属性

Bavachin is soluble in DMSO at 30 mg/mL. Bavachin is not water soluble.

基本信息

经验(实验)分子式	C₂₀H₂₀O₄
分子量	324.37
MDL编号	MFCD11617359

产品性质

测定	≥97% (HPLC)
形式	powder
储存温度	−20℃

安全信息

象形图
警示用语：	Warning
危险声明	H302 + H312 + H332
预防措施声明	P280 - P301 + P312 + P330 - P302 + P352 + P312 - P304 + P340 + P312
危险分类	Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral
储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable