产品说明
生化/生理作用
PAK7 is a PAK family kinase that contains a CDC42/Rac1 interactive binding (CRIB) motif at the N-terminus and a Ste20-like kinase domain at the C-terminus. PAK7 has been implicated in the regulation of cell morphology, motility and transformation. PAK7 is moderately expressed in adult and fetal whole brain and in all specific adult brain regions tested.
单位定义
One unit will incorporate one nanomole of phosphate into the peptide substrate CKRPRAASFAE per minute at 30 ℃ and pH 7.2 using a final concentration of 50 μM [32P] ATP.
外形
Solution in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, and 30% glycerol.
基本信息
| MDL编号 | MFCD07371026 |
| NACRES | NA.32 |
产品性质
| 质量水平 | 200 |
| 重组 | expressed in E. coli |
| 测定 | ≥75% (SDS-PAGE) |
| 形式 | buffered aqueous glycerol solution |
| specific activity | 10 units/mg protein (Bradford) |
| 分子量 | protein apparent mol wt ~116 kDa by SDS-PAGE |
| UniProt登记号 | Q9P286 |
| 运输 | dry ice |
| 储存温度 | −70℃ |
| Gene Information | human ... PAK7(57144) |
安全信息
| 储存分类代码 | 10 - Combustible liquids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |
Sigma-Aldrich
m.cnreagent.com
