产品说明
一般描述
Disulfide bonds between Cys7-Cys21, Cys14-Cys26, and Cys20-Cys33.
生化/生理作用
SNX-482 is a peptidyl toxin originally isolated from the venom of the spider Hysterocrates gigas. SNX-482 specifically blocks Cav2.3 (a1E, R-type) calcium channels in a voltage dependent manner. SNX-482 also blocks P/Q-type voltage-gated Ca2+ channels and blocks A-type K+ channels (IC50 of <3 nm).
重悬
Any aqueous buffer. Centrifuge before use (10000 x g for 5 min). After reconstitution, store for 3 months at −20 ℃ or up to four weeks at 2-8 ℃.
基本信息
| 经验(实验)分子式 | C192H274N52O60S7 |
| 分子量 | 4495.00 |
产品性质
| 质量水平 | 100 |
| 生物来源 | (from Hysterocrates gigas (African tarantula)) |
| 重组 | expressed in E. coli |
| 测定 | ≥98% (HPLC) |
| 形式 | lyophilized powder |
| 溶解性 | aqueous buffer: soluble |
| 储存温度 | −20℃ |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
