CC-401 dihydrochloride

产品名称：

CC-401 dihydrochloride
CC401
1-[5-(1H-1,2,4-Triazol-5-yl)-1H-indazol-3-yl]-3-(2-piperidinoethoxy)benzene dihydrochloride
CID 10430360
3-[3-[2-(1-Piperidinyl)ethoxy]phenyl]-5-(1H-1,2,4-triazol-5-yl)-1H-iIndazole dihydrochloride
3-(3-(2-(Piperidin-1-yl)ethoxy)phenyl)-5-(1H-1,2,4-triazol-3-yl)-1H-indazole dihydrochloride
CC 401

产品介绍：

产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

CC-401 is a cell penetrant, potent and selective c-Jun N terminal kinase (JNK) inhibitor that blocks JNK signaling in the rat obstructed kidney and inhibits renal fibrosis in the unilateral ureteral obstruction model. CC-401 in combination with chemotherapy exhibits synergism in colon cancer cell lines.

基本信息

经验(实验)分子式	C₂₂H₂₄N₆O · 2HCl
分子量	461.39
MDL编号	MFCD21364765
PubChem化学物质编号	329825499
NACRES	NA.77

产品性质

质量水平	100
测定	≥95% (HPLC)
形式	powder
颜色	white to beige
溶解性	H₂O: 10 mg/mL, clear
储存温度	−20℃
SMILES string	[H]Cl.C1(C2=NC=NN2)=CC3=C(NN=C3C4=CC=CC(OCCN5CCCCC5)=C4)C=C1
InChI	1S/C22H24N6O.ClH/c1-2-9-28(10-3-1)11-12-29-18-6-4-5-16(13-18)21-19-14-17(22-23-15-24-27-22)7-8-20(19)25-26-21;/h4-8,13-15H,1-3,9-12H2,(H,25,26)(H,23,24,27);1H
InChI key	OIBVXKYKWOUGAO-UHFFFAOYSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable