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位置:首页 > 品牌 > Sigma-Aldrich > (E)-N′-((6-(tert-butyl)-4-oxo-4H-chromen-3-yl)methylene)nicotinohydrazide

Erasin

品牌
Sigma-Aldrich
货号
SML2231
规格纯度
≥98% (HPLC)
参考价格
899.01 *本价格含增值税费
促销
服务
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  • 包邮
  • 增值税票
数量
-+
产品名称:
Erasin
(E)-N′-((6-(tert-butyl)-4-oxo-4H-chromen-3-yl)methylene)nicotinohydrazide
Erlotinib-resistance antagonizing STAT3 inhibitor
产品介绍:

产品说明

生化/生理作用

Erasin (Erlotinib-resistance antagonizing STAT3 inhibitor) is a selective inhibitor of STAT3 with selectivity over STAT5 and STAT1 in cell-based assays. It was shown to increase the apoptotic rate of HCC-827 cells with acquired resistance against Erlotinib in addition to increasing the apoptotic rate of cultured NSCLC cells in a STAT3-dependent manner.

基本信息

经验(实验)分子式C20H19N3O3
分子量349.38
NACRESNA.77

产品性质

测定≥98% (HPLC)
形式powder
颜色 white to beige
溶解性DMSO: 2 mg/mL, clear
储存温度2-8℃
SMILES stringO=C1C(/C=N/NC(C2=CC=CN=C2)=O)=COC3=CC=C(C(C)(C)C)C=C31

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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