CY-09

产品名称：

1073612-91-5
CY-09
4-[[4-Oxo-2-thioxo-3-[[3-(trifluoromethyl)phenyl]methyl]-5-thiazolidinylidene]methyl]benzoic acid

产品介绍：

产品说明

生化/生理作用

CY-09 is an NLRP3 inflammasone inhibitor. CY-09 binds directly to the ATP-binding motif of NLRP3 NACHT domain and inhibits its ATPase activity, blocking NLRP3 inflammasome assembly and activation. In mouse models CY-09 showed therapeutic effects in type 2 diabetes and cryopyrin-associated auto-inflammatory syndrome (CAPS), which is caused by gain-of-function mutations of NLRP3.

基本信息

经验(实验)分子式	C₁₉H₁₂F₃NO₃S₂
分子量	423.43
MDL编号	MFCD31714171

产品性质

测定	≥98% (HPLC)
形式	powder
颜色	faint yellow to dark orange
溶解性	DMSO: 2 mg/mL, clear
储存温度	2-8℃
SMILES string	OC(C(C=C1)=CC=C1/C=C(SC2=S)\C(N2CC3=CC=CC(C(F)(F)F)=C3)=O)=O

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable