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Febrifugine dihydrochloride

品牌
Sigma-Aldrich
CAS
32434-42-7
货号
SML0681
规格纯度
≥95% (HPLC)
参考价格
1677 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
32434-42-7
Febrifugine dihydrochloride
3-[3-[(2R,3S)-3-Hydroxy-2-piperidinyl]-2-oxopropyl]-4(3H)-quinazolinone dihydrochloride
产品介绍:

产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

Febrifugine dihydrochloride exhibits strong antimalarial activity against Plasmodium falciparum, the most insidious malaria causative agent. The adverse effects of febrifugine include diarrhoea, vomiting and liver toxicity.
Febrifugine is an antimalarial, the active component of the Chinese herb Chang Shan. Recent studies indicate that its mechanism of action is as an inhibitor of prolyl-transfer RNA synthetase (ProRS).

基本信息

经验(实验)分子式C16H19N3O3 · 2HCl
分子量374.26
PubChem化学物质编号329825583
NACRESNA.77

产品性质

质量水平100
测定≥95% (HPLC)
形式powder
旋光性[α]/D 10 to 15°, c = 1 in H2O
储存条件desiccated
颜色 off-white to gray-brown
溶解性H2O: 15 mg/mL, clear
储存温度−20℃
SMILES stringO=C1C2=CC=CC=C2N=CN1CC(C[C@@H]3[C@@H](O)CCCC3)=O.C
InChI1S/C17H20N2O3.CH4/c20-13(9-12-5-1-4-8-16(12)21)10-19-11-18-15-7-3-2-6-14(15)17(19)22;/h2-3,6-7,11-12,16,21H,1,4-5,8-10H2;1H4/t12-,16+;/m1./s1
InChI keySNTOTCUGCWLHEZ-KKJWGQAZSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H302
危险分类Acute Tox. 4 Oral
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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