产品说明
包装
5, 25 mg in glass bottle
生化/生理作用
Febrifugine dihydrochloride exhibits strong antimalarial activity against Plasmodium falciparum, the most insidious malaria causative agent. The adverse effects of febrifugine include diarrhoea, vomiting and liver toxicity.
Febrifugine is an antimalarial, the active component of the Chinese herb Chang Shan. Recent studies indicate that its mechanism of action is as an inhibitor of prolyl-transfer RNA synthetase (ProRS).
基本信息
| 经验(实验)分子式 | C16H19N3O3 · 2HCl |
| 分子量 | 374.26 |
| PubChem化学物质编号 | 329825583 |
| NACRES | NA.77 |
产品性质
| 质量水平 | 100 |
| 测定 | ≥95% (HPLC) |
| 形式 | powder |
| 旋光性 | [α]/D 10 to 15°, c = 1 in H2O |
| 储存条件 | desiccated |
| 颜色 | off-white to gray-brown |
| 溶解性 | H2O: 15 mg/mL, clear |
| 储存温度 | −20℃ |
| SMILES string | O=C1C2=CC=CC=C2N=CN1CC(C[C@@H]3[C@@H](O)CCCC3)=O.C |
| InChI | 1S/C17H20N2O3.CH4/c20-13(9-12-5-1-4-8-16(12)21)10-19-11-18-15-7-3-2-6-14(15)17(19)22;/h2-3,6-7,11-12,16,21H,1,4-5,8-10H2;1H4/t12-,16+;/m1./s1 |
| InChI key | SNTOTCUGCWLHEZ-KKJWGQAZSA-N |
安全信息
| 象形图 |  |
| 警示用语： | Warning |
| 危险声明 | H302 |
| 危险分类 | Acute Tox. 4 Oral |
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
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