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KR-32568

品牌
Sigma-Aldrich
CAS
852146-73-7
货号
K4389
规格纯度
≥98% (HPLC), solid
参考价格
2209 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
852146-73-7
KR-32568
[5-(2-Methyl-5-fluorophenyl)furan-2-ylcarbonyl]guanidine
产品介绍:

产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

Sodium/hydrogen exchanger-1 (NHE-1) inhibitor; IC50 = 0.23 μM; inhibited NHE-1-mediated rabbit platelet swelling; in anesthetized rats, reduced infarct size from 67% (control) to 43% (at 0.1 mg/kg) and 24% (at 1.0 mg/kg); reduced number of ventricular premature beats from 530 to 266 (at 0.1 mg/kg) and 115 (at 1.0 mg/kg); reduced ventricular fibrillation incidence from 17 to 8 (0.1 mg/kg) and 0 (1.0 mg/kg); implications for research and treatment of myocardial ischemic diseases.

基本信息

经验(实验)分子式C13H12FN3O2
分子量261.25
MDL编号MFCD08705324
PubChem化学物质编号24724522
NACRESNA.77

产品性质

质量水平100
测定≥98% (HPLC)
形式solid
颜色 white
溶解性DMSO: ~10 mg/mL
储存温度2-8℃
SMILES stringCc1ccc(F)cc1-c2ccc(o2)C(=O)NC(N)=N
InChI1S/C13H12FN3O2/c1-7-2-3-8(14)6-9(7)10-4-5-11(19-10)12(18)17-13(15)16/h2-6H,1H3,(H4,15,16,17,18)
InChI keyDTLDHYBZLVASJQ-UHFFFAOYSA-N
Gene Informationhuman ... SLC9A1(6548)

安全信息

象形图GHS07
警示用语:Warning
危险声明H302 - H315 - H319 - H335
预防措施声明P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
危险分类Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码10 - Combustible liquids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Sigma-Aldrich

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