Tarocin A1

产品名称：

Tarocin A1
(4S,5R)-5-(3,5-bis(trifluoromethyl)phenyl)-3-(3-(isoquinolin-4-yl)propanoyl)-4-methyloxazolidin-2-one

产品介绍：

产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

Tarocin A1 is an oxazolidinone which inhibits TarO, the first enzyme in teichoic acid synthesis. Tarocin A1 has an IC₅₀ value of 40 nM in a biochemical TarO assay. Tarocin A does not inhibit bacterial growth alone, and exhibits no cytotoxicity against HeLa cells, but it has potent bactericidal syergism with broad spectrum β-lactams, and may restore the clinical efficacy of existing β-lactam antibiotics.

基本信息

经验(实验)分子式	C₂₄H₁₈F₆N₂O₃
分子量	496.40
PubChem化学物质编号	329826010

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	white to beige
溶解性	DMSO: 20 mg/mL, clear
储存温度	2-8℃
SMILES string	C[C@H](N1C(CCC2=C(C=CC=C3)C3=CN=C2)=O)[C@@H](C4=CC(C(F)(F)F)=CC(C(F)(F)F)=C4)OC1=O
InChI	1S/C24H18F6N2O3/c1-13-21(16-8-17(23(25,26)27)10-18(9-16)24(28,29)30)35-22(34)32(13)20(33)7-6-15-12-31-11-14-4-2-3-5-19(14)15/h2-5,8-13,21H,6-7H2,1H3/t13-,21-/m0/s1
InChI key	XWMRKUPNQVITEC-ZSEKCTLFSA-N

安全信息

象形图
警示用语：	Warning
危险声明	H315 - H319 - H335
预防措施声明	P302 + P352 - P305 + P351 + P338
危险分类	Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官	Respiratory system
储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable