SU 4312

产品名称：

5812-07-7
SU 4312
3-(4-Dimethylaminobenzylidenyl)-2-indolinone
3-[[(4-Dimethyl-amino)phenyl]methylene]-1,3-dihydro-2H-indol-2-one, E/Z mixture

产品介绍：

产品说明

应用

SU 4312 was used to study angiogenesis during development of zebrafish embryos.²

包装

5 mg in glass bottle

生化/生理作用

SU 4312 inhibits the neuronal NOS and exhibits neuroprotection against NO-mediated neurotoxicity. It might be effective in treatment of neurodegenerative disorders.¹
SU 4312 is a vascular endothelial growth factor (VEGF) receptor protein tyrosine kinase 1/2 and platelet derived growth factor (PDGF) receptor inhibitor.

特点和优势

This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

其他说明

This product is a mixture of the cis- and trans- isomers. The ratio is about 55:45 based on HPLC.

基本信息

经验(实验)分子式	C₁₇H₁₆N₂O
分子量	264.32
MDL编号	MFCD00118147
PubChem化学物质编号	24278803

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	orange
溶解性	DMSO: >10 mg/mL H₂O: insoluble
储存温度	2-8℃
SMILES string	CN(C)c1ccc(cc1)\C=C2\C(=O)Nc3ccccc23
InChI	1S/C17H16N2O/c1-19(2)13-9-7-12(8-10-13)11-15-14-5-3-4-6-16(14)18-17(15)20/h3-11H,1-2H3,(H,18,20)/b15-11+
InChI key	UAKWLVYMKBWHMX-RVDMUPIBSA-N
Gene Information	human ... FLT1(2321)

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	dust mask type N95 (US), Eyeshields, Gloves