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JTV-519 hemifumarate

品牌
Sigma-Aldrich
CAS
145903-06-6
货号
SML0549
规格纯度
≥98% (HPLC)
参考价格
1525.52 *本价格含增值税费
促销
服务
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  • 包邮
  • 增值税票
数量
-+
产品名称:
145903-06-6
JTV-519 hemifumarate
K201 hemifumarate
1-(2,3-Dihydro-7-methoxy-1,4-benzothiazepin-4(5H)-yl)-3-[4-(phenylmethyl)-1-piperidinyl]-1-propanone hemifumarate
产品介绍:

产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

JTV-519 is a potent inhibitor or the ryanodine receptor 2 (RYR2) blocker. RYR2 is a cardiac calcium channel that regulates calcium levels in the sarcoplasmic reticulum. JTV-519 stabilizes RYR2 in the closed state.

特点和优势

This compound is featured on the InsP3/Ryanodine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

基本信息

经验(实验)分子式C25H32N2O2S · .5C4H4O4
分子量482.63
MDL编号MFCD23098915
PubChem化学物质编号329825545
NACRESNA.77

产品性质

质量水平100
测定≥98% (HPLC)
形式powder
储存条件desiccated
颜色 white to beige
溶解性DMSO: 10 mg/mL, clear
储存温度2-8℃
SMILES stringOC(=O)\C=C\C(O)=O.COc1ccc2SCCN(Cc2c1)C(=O)CCN3CCC(CC3)Cc4ccccc4.COc5ccc6SCCN(Cc6c5)C(=O)CCN7CCC(CC7)Cc8ccccc8
InChI1S/2C25H32N2O2S.C4H4O4/c2*1-29-23-7-8-24-22(18-23)19-27(15-16-30-24)25(28)11-14-26-12-9-21(10-13-26)17-20-5-3-2-4-6-20;5-3(6)1-2-4(7)8/h2*2-8,18,21H,9-17,19H2,1H3;1-2H,(H,5,6)(H,7,8)/b;;2-1+
InChI keyMNAIJOCDPCXVEY-WXXKFALUSA-N

安全信息

象形图GHS09
警示用语:Warning
危险声明H410
预防措施声明P273 - P501
危险分类Aquatic Acute 1 - Aquatic Chronic 1
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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