产品说明
应用
5-Fluoro-2′-deoxyuridine 5′-monophosphate sodium salt has been used as an anti-mitotic agent and is used extensively in studies on the activity and function of thymidylate synthase (TS).
包装
5 mg in glass bottle
25 mg in poly bottle
生化/生理作用
5-Fluoro-2′-deoxyuridine 5′-monophosphate sodium salt (FdUMP) is an DNA synthesis inhibitor. FdUMP along with RNA synthesis inhibitor 3′-C-ethinylcytidine induces cell death in cervical cancer cells at nanomolar concentrations.
基本信息
| 经验(实验)分子式 | C9H12FN2O8P |
| 分子量 | 326.17 |
| MDL编号 | MFCD00057409 |
| PubChem化学物质编号 | 24894845 |
| NACRES | NA.51 |
产品性质
| 质量水平 | 200 |
| 测定 | ~85% |
| 形式 | solid |
| 储存温度 | −20℃ |
| SMILES string | [Na].OC1CC(OC1COP(O)(O)=O)N2C=C(F)C(=O)NC2=O |
| InChI | 1S/C9H12FN2O8P.Na.H/c10-4-2-12(9(15)11-8(4)14)7-1-5(13)6(20-7)3-19-21(16,17)18;;/h2,5-7,13H,1,3H2,(H,11,14,15)(H2,16,17,18);; |
| InChI key | DGEOOGBABXVZPJ-UHFFFAOYSA-N |
安全信息
| 象形图 |   |
| 警示用语： | Warning |
| 危险声明 | H302 + H312 + H332 - H351 |
| 预防措施声明 | P201 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 - P308 + P313 |
| 危险分类 | Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 2 |
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
Sigma-Aldrich
m.cnreagent.com
