Actinonin

产品名称：

13434-13-4
Actinonin
3-[[1-[(2-(Hydroxymethyl)-1-pyrrolidinyl)carbonyl]-2-methylpropyl]carbamoyl]octanohydroxamic acid

产品介绍：

产品说明

一般描述

Chemical structure: peptide

应用

Actinonin has been used as a control to inhibit meprin-β activity in C57BL/6 mice. It has also been used to study the high-affinity interaction of EcPDF with actinonin by 15N NMR spectroscopy and isothermal titration.

包装

10 mg in glass bottle
25 mg in poly bottle

生化/生理作用

Actinonin has inhibitory action against peptide deformylase (PDF). It is effective against Gram-positive and fastidious Gram-negative microorganisms.
Actinonin is an inhibitor of leucine aminopeptidase. Actinonin has also been used to improve antibacterial activity and antiobesity therapeutics.

特点和优势

This compound is featured on the Neuropeptidases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

基本信息

经验(实验)分子式	C₁₉H₃₅N₃O₅
分子量	385.50
Beilstein	1555250
MDL编号	MFCD00080257
PubChem化学物质编号	24278232
NACRES	NA.77

产品性质

质量水平	200
生物来源	synthetic (organic)
测定	≥98% (TLC)
形式	powder
溶解性	ethanol: 50 mg/mL, clear, colorless
作用机制	enzyme \| inhibits
抗生素抗菌谱	Gram-negative bacteria Gram-positive bacteria
储存温度	−20℃
SMILES string	CCCCCC(CC(=O)NO)C(=O)NC(C(C)C)C(=O)N1CCCC1CO
InChI	1S/C19H35N3O5/c1-4-5-6-8-14(11-16(24)21-27)18(25)20-17(13(2)3)19(26)22-10-7-9-15(22)12-23/h13-15,17,23,27H,4-12H2,1-3H3,(H,20,25)(H,21,24)
InChI key	XJLATMLVMSFZBN-UHFFFAOYSA-N
Gene Information	human ... ANPEP(290), DPP4(1803), ECE1(1889), LAP3(51056)

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, type N95 (US)