产品说明
一般描述
Madecassoside is one of the major pentacyclic triterpenoid saponin compounds extracted from Centella asiatica.
应用
Madecassoside has been used to study its cytotoxic effects on mouse macrophage cell lines (J774A.1). It has also been used as a potential inhibitor of serine racemase (SR) for in vitro and ex vivo studies.
包装
10 mg in glass bottle
50 mg in poly bottle
生化/生理作用
羟基积雪草苷是在积雪草(Gotu kola)中发现的一种三萜类化合物,积雪草是一种用于中药(TCM)、印度草药和非洲传统药物的草药。羟基积雪草苷具有广泛的生物学活性,包括抗炎、伤口愈合和抗氧化活性。据报道其可通过抑制ERK、p38和NF-κB活性来抑制LPS诱导的TNF-α的产生。
Madecassoside has skin hydration properties. It is a well-known collagen inducer that exerts anti-aging and anti-rheumatoid arthritis effects. Madecassoside also elicits neuroprotective activities.
基本信息
经验(实验)分子式 | C48H78O20 |
分子量 | 975.12 |
EC 号 | 252-076-1 |
NACRES | NA.25 |
产品性质
质量水平 | 200 |
测定 | ≥95% (HPLC) |
形式 | powder |
颜色 | white to off-white |
溶解性 | H2O: 1 mg/mL, clear, colorless |
储存温度 | 2-8℃ |
InChI | 1S/C48H78O20/c1-19-10-11-48(13-12-46(6)22(28(48)20(19)2)8-9-27-44(4)14-24(52)39(61)45(5,18-50)38(44)23(51)15-47(27,46)7)43(62)68-42-35(59)32(56)30(54)26(66-42)17-63-40-36(60)33(57)37(25(16-49)65-40)67-41-34(58)31(55)29(53)21(3)64-41/h8,19-21,23-42,49-61H,9-18H2,1-7H3 |
InChI key | BNMGUJRJUUDLHW-UHFFFAOYSA-N |
安全信息
储存分类代码 | 11 - Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich