产品说明
一般描述
Lysine acetyltransferase 8 (KAT8) or MYST histone acetyltransferase 1 (MYST1) is a signaling protein that belongs to the MYST family of histone acetyl transferases (HATs). MYST1 has a chromodomain that is involved in protein-protein interactions and targeting transcriptional regulators to the chromatin.
生化/生理作用
Lysine acetyltransferase 8 (KAT8) or MYST histone acetyltransferase 1 (MYST1) was originally isolated as a human immunodeficiency virus-1 (HIV-1) TAT-interactive protein, which plays important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and non-histone proteins. MYST1 is also involved in ataxia-telangiectasia mutated (ATM) function. It acetylates histone 4-lysine 16 (H4K16). The protein is a modulator of embryonic stem cells and an epigenetic regulator. It has been associated with gastric carcinoma.
外形
Supplied in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
制备说明
after opening, aliquot into smaller quantities and store at -70 ℃. Avoid repeating handling and multiple freeze/thaw cycles
基本信息
| NACRES | NA.32 |
产品性质
| 生物来源 | human |
| 重组 | expressed in baculovirus infected Sf9 cells |
| 测定 | ≥70% (SDS-PAGE) |
| 形式 | buffered aqueous glycerol solution |
| 分子量 | ~83 kDa |
| NCBI登记号 | BC037773 |
| application(s) | cell analysis |
| 运输 | dry ice |
| 储存温度 | −70℃ |
| Gene Information | human ... KAT8(84148) |
安全信息
| 储存分类代码 | 10 - Combustible liquids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
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