产品说明
一般描述
PSMC5 (proteasome 26S subunit, ATPase, 5) is a regulatory subunit of the 26S proteasome belonging to the family of putative ATPases. It has structural homology with yeast Sug1p gene.
免疫原
Immunogen Sequence: GI # 24497435, sequence 2-160
Recombinant proteasome 26S ATPase subunit 5
应用
Anti-PSMC5 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.
生化/生理作用
26S protease regulatory subunit 8 is an enzyme encoded by the PSMC5 gene in humans and is important for the transcription of MHC II molecules. It has a role in regulating transcription of class I MHC and the MHC II-like molecules, HLA-DM and HLA-DO. PSMC5 acts as a key regulator of collagen contraction in primary human lung fibroblasts (a functional characteristic of myofibroblasts) and is a critical step in the process of fibrosis.
外形
Solution in phosphate buffered saline containing 0.02% sodium azide.
基本信息
NACRES | NA.41 |
产品性质
生物来源 | chicken |
偶联物 | unconjugated |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
形式 | buffered aqueous solution |
species reactivity | rat, human |
manufacturer/tradename | Genway 15-288-22829 |
technique(s) | western blot: suitable |
NCBI登记号 | NP_002796.4 |
UniProt登记号 | P62195 |
运输 | wet ice |
储存温度 | −20℃ |
Gene Information | human ... PSMC5(5705) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
个人防护装备 | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |
Sigma-Aldrich