Anti-RGS18 antibody produced in chicken

产品说明

免疫原

Recombinant regulator of G-protein signalling 18
Immunogen Sequence: GI # 18640750, sequence 11-100

应用

Anti-RGS18 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

生化/生理作用

Regulator of G-protein signaling 18 is a protein encoded by the RGS18 gene in humans. It is a GTPase-activating protein for the G-α-q and G-α-i subunits of heterotrimeric G-proteins that turns off signaling by G-protein coupled receptors. It is highly expressed in platelets. RGS18 can act on G(q)-mediated signaling pathways. It is expressed most highly in megakaryocytes and can modulate GPCR pathways in both mammalian and yeast cells. RGS18 may have an important role in the regulation of megakaryocyte differentiation and chemotaxis.

外形

Solution in phosphate buffered saline containing 0.02% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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