Caspase-8 Inhibitor I, Cell-Permeable-Calbiochem

产品说明

一般描述

Potent, cell-permeable and reversible inhibitor of caspase-8 and Granzyme B.
A potent, cell-permeable, and reversible inhibitor of caspase-8 and Granzyme B. The N-terminal sequence (amino acids 1-16) corresponds to the hydrophobic region of the signal peptide of Kaposi fibroblast growth factor and confers cell permeability to the peptide.

包装

1 mg in Plastic ampoule

生化/生理作用

Cell permeable: yes
Primary Target
caspase-8
Product does not compete with ATP.
Reversible: yes

警告

Toxicity: Standard Handling (A)

序列

Ac-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Ile-Glu-Thr-Asp-CHO

重悬

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

其他说明

Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
Hamada, E., et al. 1990. J. Hepatol. 30, 807.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

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安全信息