Cathepsin B Inhibitor II-Calbiochem

产品说明

一般描述

Note: this peptide forms cyclic isomers.
Lysinal analog of Leupeptin (Cat. No. 108975). A more potent inhibitor of cathepsin B (IC₅₀ = 4 nM) than of leupeptin (IC₅₀ = 310 nM). Note: this peptide forms cyclic isomers.
A more active lysinal analog of Leupeptin (Cat. No. 108975). A more potent inhibitor of cathepsin B (IC₅₀ = 4 nM) compared to leupeptin (IC₅₀ = 310 nM).

包装

1 mg in Plastic ampoule

生化/生理作用

Product does not compete with ATP.
Primary Target
cathepsin B
Reversible: no
Target IC₅₀: 4 nM against cathepsin B
Cell permeable: no

警告

Toxicity: Standard Handling (A)

序列

Ac-Leu-Val-lysinal

重悬

Following reconstitution aliquot and freeze (-70°C). Stock solutions are stable for up to 1 month at -70°C.

其他说明

McConnell, R.M., et al. 1993. J. Med. Chem. 36, 1084.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

产品性质

安全信息