产品说明
一般描述
By ELISA, the antibody shows approximately 50% cross-reactivity with recombinant human ephrin-A5 and no cross-reactivity with recombinant mouse ephrin-A1, mouse ephrin-A2, human ephrin-A3, mouse ephrin-B1, mouse ephrin-B2, and mouse ephrin B3.
免疫原
recombinant human ephrin-A4, extracellular domain, expressed in NSO cells.
生化/生理作用
Ephrin A4 binds to EPH receptor A4, a protein-tyrosine kinase family that belongs to the ephrin receptor subfamily. The ephrin-A and ephrin-B ligands and regulate developmental events, particularly those of the nervous system. EphrinA4 regulates the axonal growth, astrocyte reactivity and neuroinflammation in experimental autoimmune encephalomyelitis. High expression of EphA4 receptor correlates with tumor progression, invasion and metastasis of gastric cancer and is a suitable prognostic marker.
外形
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline.
基本信息
| MDL编号 | MFCD02096316 |
| NACRES | NA.41 |
产品性质
| 质量水平 | 200 |
| 生物来源 | goat |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | lyophilized powder |
| species reactivity | human |
| technique(s) | indirect ELISA: 0.5-1.0 μg/mL western blot: 0.1-0.2 μg/mL |
| UniProt登记号 | P52798 |
| 储存温度 | −20℃ |
| Gene Information | human ... EFNA4(1945) |
Sigma-Aldrich
m.cnreagent.com
