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Anti-phospho-Retinoblastoma (pSer811) antibody produced in rabbit

品牌
Sigma-Aldrich
货号
R4278
规格纯度
affinity isolated antibody, buffered aqueous solution
参考价格
4731.57 *本价格含增值税费
促销
服务
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  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-phospho-Retinoblastoma (pSer811) antibody produced in rabbit
Anti-phospho-Rb (pSer811)
产品介绍:

产品说明

一般描述

Retinoblastoma (Rb) is a pediatric intraocular neoplasm caused due to the biallelic inactivation of the RB1 gene. Retinoblastoma is also known as RB1 (RB transcriptional corepressor 1). It is located on human chromosome 13q14. It is a tumor suppressor gene.

免疫原

synthetic phosphopeptide derived from the region of human Rb that contains Ser811.

生化/生理作用

Retinoblastoma (RB) interacts with several protein factors to control the expression of target genes which promote cell cycle arrest, apoptosis, and differentiation. It helps to modulate nucleosome and chromatin structures. Absence of RB induces prostate cancer metastasis.

外形

Solution in Dulbecco′s phosphate buffered saline (without Mg2+ and Ca2+), pH 7.3, with 1.0 mg/mL BSA (IgG and protease free) and 0.05% sodium azide.

基本信息

MDL编号MFCD06411917

产品性质

生物来源rabbit
质量水平200
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
species reactivityhuman, mouse, rat
technique(s)western blot: 0.5-1.5 μg/mL using Jurkat cells in high growth phase.
UniProt登记号P06400
运输dry ice
储存温度−70℃
Gene Informationhuman ... RB1(5925)
mouse ... Rb1(19645)
rat ... Rb1(24708)

Sigma-Aldrich

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