Estra-1,3,5(10)triene-3,17в-diol 3-[N,N-bis(2-chloroethyl)carbamate] 17-(dihydrogen phosphate) sodium salt

产品名称：

52205-73-9
Estramustine sodium phosphate
Estra-1,3,5(10)triene-3,17в-diol 3-[N,N-bis(2-chloroethyl)carbamate] 17-(dihydrogen phosphate) sodium salt
Estradiol 3-bis(2-chloroethyl)carbamate 17-(dihydrogen phosphate) sodium salt

产品介绍：

产品说明

包装

5 mg in glass insert
25 mg in poly bottle

生化/生理作用

Estradiol mustard prodrug, which binds estradiol receptors irreversibly. Highly effective in treatment of advanced metastatic prostate cancer. Depolymerizes microtubules by binding to microtubule associated proteins (MAPs).

基本信息

经验(实验)分子式	C₂₃H₃₀Cl₂NNa₂O₆P
分子量	564.35
EC 号	257-735-7
MDL编号	MFCD00866320
PubChem化学物质编号	329798968

产品性质

测定	≥85.0% (HPLC)
质量水平	100
形式	powder
溶解性	H₂O: 50 mg/mL
运输	ambient
储存温度	room temp
SMILES string	[H][C@]12[C@@]([C@@](CC[C@@H]3OP([O-])([O-])=O)([H])[C@]3(C)CC2)([H])CCC4=C1C=CC(OC(N(CCCl)CCCl)=O)=C4.[Na+].[Na+]
InChI	1S/C23H32Cl2NO6P.2Na/c1-23-9-8-18-17-5-3-16(31-22(27)26(12-10-24)13-11-25)14-15(17)2-4-19(18)20(23)6-7-21(23)32-33(28,29)30;;/h3,5,14,18-21H,2,4,6-13H2,1H3,(H2,28,29,30);;/q;2*+1/p-2/t18-,19-,20+,21+,23+;;/m1../s1
InChI key	IIUMCNJTGSMNRO-VVSKJQCTSA-L
Gene Information	human ... ESR2(2100)

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	dust mask type N95 (US), Eyeshields, Gloves