HX531

产品名称：

188844-34-0
HX531
HX-531
4-(5H-2,3-(2,5-dimethyl-2,5-hexano)-5-methyl- 8-nitrodibenzo[b,e][1,4]diazepin-11-yl)benzoic acid
4-(7,8,9,10-Tetrahydro-5,7,7,10.10-pentamethyl-2-nitro-5H-benzo[b]naphtho[2,3-e][1,4]-diazepin-12-yl)-benzoic acid
HX 531

产品介绍：

产品说明

生化/生理作用

HX-531 is a potent antagonist of the retinoid X receptor (RXR) with an IC50 value of 18 nM. HX531 has been used in many studies of the various effects of retinoids and RXR activity in diseases such as diabetes, Parkinson′s disease, often as a control for agonists such as Bexarotene. It was recently shown to promote white adipogenic differentiation and inhibit both basal and Bexarotene-induced brown adipogenic differentiation.

基本信息

经验(实验)分子式	C₂₉H₂₉N₃O₄
分子量	483.56
MDL编号	MFCD19690920
NACRES	NA.77

产品性质

测定	≥98% (HPLC)
形式	powder
颜色	yellow to orange
溶解性	DMSO: 2 mg/mL, clear
储存温度	2-8℃
SMILES string	CN(C1=CC2=C(C(C)(CCC2(C)C)C)C=C13)C(C=C4)=C(N=C3C5=CC=C(C=C5)C(O)=O)C=C4[N+]([O-])=O

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable