PF-2545920 hydrochloride

产品名称：

898562-94-2
PF-2545920 hydrochloride
PF-920 hydrochloride
2-[4-(1-Methyl-4-pyridin-4-yl-1H-pyrazol-3-yl)-phenoxymethyl]-quinoline hydrochloride
MP-10 hydrochloride
PF-02545920 hydrochloride

产品介绍：

产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

PF-2545920 hydrochloride (MP-10) is a potent and selective cyclic nucleotide phosphodiesterase (PDE) 10A competitive inhibitor with a reported IC₅₀ value of 1.26 nM. PDE10A hydrolyzes both cAMP and cGMP, and is highly expressed in medium spiny neurons of the mammalian striatum and in basal ganglia areas where D1 and D2 dopamine receptors are expressed. PF-2545920 has been studied for treatment of schizophrenia and Huntington′s disease.

法律信息

Sold for research purposes under agreement from Pfizer Inc.
Pfizer is a registered trademark of Pfizer, Inc.

基本信息

经验(实验)分子式	C₂₅H₂₀N₄O · HCl
分子量	428.91
MDL编号	MFCD30489759
NACRES	NA.77

产品性质

质量水平	100
测定	≥97% (HPLC)
形式	powder
manufacturer/tradename	Pfizer^®
颜色	white to brown
溶解性	DMSO: 20 mg/mL, clear
创始人	Pfizer
储存温度	room temp
SMILES string	CN1C=C(C2=CC=NC=C2)C(C(C=C3)=CC=C3OCC4=NC5=CC=CC=C5C=C4)=N1.[H]Cl

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable